Yes, orb-weaver spiders are venomous. However, most orb-weaver spiders are not considered to be dangerous to humans. As a parallel, bees are also venomous but generally are not considered dangerous to humans. Orb weaver’s venom is primarily designed to immobilize and digest small insects and other arthropods that get caught in their intricate orb-shaped webs. While orb-weaver spider bites can cause localized pain, redness, and swelling, they are generally not considered medically significant or life-threatening to humans. It’s always a good idea to exercise caution and avoid disturbing or provoking any spider, but orb-weavers are generally considered harmless to humans.